Joseph A. Kanabrocki

Laboratory safety, especially biosafety, is a critical component of research activities conducted in the Biological Sciences Division at the University of Chicago (UC), including infectious diseases research conducted in UC laboratories located either in Hyde Park or at the Howard T. Ricketts Biocontainment Laboratory, a regional biocontainment lab located on the campus of Argonne National Laboratories. Standard operating procedures and research-related protocols are developed with safety as a primary objective. Whenever possible, we incorporate empirical data into our risk assessment process to optimize safety while at the same time minimizing procedures that might potentially disrupt or unnecessarily complicate primary research activities. Unfortunately, empirical biosafety data is, in many cases, unavailable. My group is interested in exploring these basic research-related biosafety questions. To this end, we have established an applied biosafety research program which is included as part of a post-doctoral fellowship program designed to train post-graduate level scientists (Ph.D., M.D., D.V.M.) on how to manage biosafety programs at major academic, government, or industry-related research institutes.

University of Notre Dame
Indiana
B.S. - Biology

University of South Dakota School of Medicine
South Dakota
Ph.D. - Microbiology

Hereditary hemochromatosis restores the virulence of plague vaccine strains.
Hereditary hemochromatosis restores the virulence of plague vaccine strains. J Infect Dis. 2012 Oct 01; 206(7):1050-8.
PMID: 22896664

Policy: Adaptations of avian flu virus are a cause for concern.
Policy: Adaptations of avian flu virus are a cause for concern. Nature. 2012 Jan 31; 482(7384):153-4.
PMID: 22294204

Public health and biosecurity. Adaptations of avian flu virus are a cause for concern.
Public health and biosecurity. Adaptations of avian flu virus are a cause for concern. Science. 2012 Feb 10; 335(6069):660-1.
PMID: 22294736

Interactions between biocontainment laboratories and their communities: a successful work in progress.
Interactions between biocontainment laboratories and their communities: a successful work in progress. Trends Microbiol. 2011 May; 19(5):209-10.
PMID: 21353566

Transformation of Paramecium tetraurelia by electroporation or particle bombardment.
Transformation of Paramecium tetraurelia by electroporation or particle bombardment. J Eukaryot Microbiol. 1999 Jan-Feb; 46(1):56-65.
PMID: 10188261

In vivo Paramecium mutants show that calmodulin orchestrates membrane responses to stimuli.
In vivo Paramecium mutants show that calmodulin orchestrates membrane responses to stimuli. Cell Calcium. 1992 Jun-Jul; 13(6-7):413-25.
PMID: 1380404

Efficient transformation of cam2, a behavioral mutant of Paramecium tetraurelia, with the calmodulin gene.
Efficient transformation of cam2, a behavioral mutant of Paramecium tetraurelia, with the calmodulin gene. Proc Natl Acad Sci U S A. 1991 Dec 01; 88(23):10845-9.
PMID: 1961754

Efficient expression of the Paramecium calmodulin gene in Escherichia coli after four TAA-to-CAA changes through a series of polymerase chain reactions.
Efficient expression of the Paramecium calmodulin gene in Escherichia coli after four TAA-to-CAA changes through a series of polymerase chain reactions. J Protozool. 1991 Sep-Oct; 38(5):441-7.
PMID: 1920142

Circadian distribution of proteins in urine from healthy young men.
Circadian distribution of proteins in urine from healthy young men. Chronobiol Int. 1990; 7(5-6):433-43.
PMID: 2097077

Comparative study of refractile (R) bodies and their genetic determinants: relationship of type 51 R bodies to R bodies produced by Pseudomonas taeniospiralis.
Comparative study of refractile (R) bodies and their genetic determinants: relationship of type 51 R bodies to R bodies produced by Pseudomonas taeniospiralis. J Bacteriol. 1986 Nov; 168(2):1019-22.
PMID: 3782012

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