Philip Verhoef, M.D., Ph.D.

APPOINTMENTS

  • Assistiant Professor, Department of Medicine and Pediatrics, Section of Pulmonary / Critical Care, Committee on Immunology

​EDUCATION

Ph.D., Case Western Reserve University, Cleveland, OH, 2004
M.D., Case Western Reserve University, Cleveland, OH, 2005

CONTACT INFORMATION

The University of Chicago
BSLC R014
924 East 57th Street
Chicago, IL  60637

Phone: (773) 702-834-5079

pverhoef@uchicago.edu

RESEARCH SUMMARY

Dr. Verhoef is a physician-scientist interested in immune dysfunction in the ICU. His K08-funded research focuses on the hypothesis that type 2 (allergic) immunity plays a critical pro-resolving, anti-inflammatory role during acute infection. His laboratory employs the entire spectrum of basic, translational, informatic, and clinical approaches. First, he uses mouse models of Staphylococcus aureus sepsis to understand how type 2 immunity protects against sepsis lethality; second, he is continuing a project started by fellowship graduate Jared Greenberg (now at Rush University) in which blood from septic patients with Staphylococcus aureus bacteremia is collected at various time points and analyzed for markers of immune function; and finally, in collaboration with Medicine faculty like Matthew Churpek and Andrey Rzhetsky, he is analyzing large electronic datasets to understand how the presence of comorbid immunologic diseases modifies the course of infection and sepsis. His long term objective is to bring rigorous immunologic analysis to the care of critically ill patients