Howard Halpern, MD PhD

Howard J. Halpern, MD, PhD, specializes in medical imaging techniques. He is an expert in very low frequency-imaging-electron paramagnetic resonance (VLF-I-EPR). This technique enables measurement of changes in oxygen content in tumor tissues--a key determinant of response to radiation therapy.



Dr. Halpern is the co-author of a textbook on free radical biology. He serves as the principal investigator for the Oversight Committee for the Laboratory Training of Radiation Oncology Residents.

University of Wisconsin
Madison, Wisconsin
PhD - High Energy Physics
1976

University of Miami
Miami, Florida
MD - Medicine
061980

Sensing and Imaging Molecular Oxygen in Mammals with Spin Lattice Relaxation Electron Paramagnetic Resonance.
Sensing and Imaging Molecular Oxygen in Mammals with Spin Lattice Relaxation Electron Paramagnetic Resonance. Mol Imaging Biol. 2024 Mar 28.
PMID: 38548994

Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI.
Accurate reconstruction of 4D spectral-spatial images from sparse-view data in continuous-wave EPRI. J Magn Reson. 2024 Mar 12; 361:107654.
PMID: 38492546

Directional TV algorithm for fast EPR imaging.
Directional TV algorithm for fast EPR imaging. J Magn Reson. 2024 Mar 01; 361:107652.
PMID: 38457937

Corrigendum: Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models.
Corrigendum: Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models. Front Med (Lausanne). 2023; 10:1339872.
PMID: 38116039

Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models.
Absolute oxygen-guided radiation therapy improves tumor control in three preclinical tumor models. Front Med (Lausanne). 2023; 10:1269689.
PMID: 37904839

A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module.
A Preclinical Positron Emission Tomography (PET) and Electron-Paramagnetic-Resonance-Imaging (EPRI) Hybrid System: PET Detector Module. IEEE Trans Radiat Plasma Med Sci. 2023 Nov; 7(8):794-801.
PMID: 37981977

Direct Measurement and Imaging of Redox Status with Electron Paramagnetic Resonance.
Direct Measurement and Imaging of Redox Status with Electron Paramagnetic Resonance. Antioxid Redox Signal. 2023 May 04.
PMID: 36680741

A Simple but Universal Fully Linearized ADMM Algorithm for Optimization Based Image Reconstruction.
A Simple but Universal Fully Linearized ADMM Algorithm for Optimization Based Image Reconstruction. Res Sq. 2023 Apr 28.
PMID: 37162853

4D-image reconstruction directly from limited-angular-range data in continuous-wave electron paramagnetic resonance imaging.
4D-image reconstruction directly from limited-angular-range data in continuous-wave electron paramagnetic resonance imaging. J Magn Reson. 2023 May; 350:107432.
PMID: 37058955

An iterative reconstruction algorithm without system matrix for EPR imaging.
An iterative reconstruction algorithm without system matrix for EPR imaging. J Magn Reson. 2022 Nov; 344:107307.
PMID: 36308904

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